Two and a Half Men
Twelve seasons on a Malibu beach house, opened by four sung syllables.
Two and a Half Men kept one opening title sequence, 25 seconds long, across season 6.
At 25 seconds, it opens well under the 38-second median for comedy sequences in this catalogue.
It arrived on CBS in 2003, when Candid Camera, Guiding Light and As the World Turns were also on the network.
The opening titles
Season 6
25sFan upload dated to 2008, so the sixth season rather than the first.
More comedy opening titles from the 2000s
1 sequence
The Big Bang Theory
Fourteen billion years of natural history in twenty-three seconds, flashing past at one image per beat.
- Season 1
1 sequence
Malcolm in the Middle
They Might Be Giants' 'Boss of Me' over archive film of chaos — falling, crashing and general misadventure, cut faster than a network comedy usually dares.
- Season 1
1 sequence
The Office
Scranton, a car park and a filing cabinet, shot like stock footage for a regional business — twenty-two seconds that promise nothing will happen.
- Season 1
1 sequence
Scrubs
Twelve seconds, an X-ray and a guitar — a medical comedy that spends less time on titles than most shows spend on a network ident.
- Season 1
1 sequence
It's Always Sunny in Philadelphia
Photographs of Philadelphia over a jaunty public-domain waltz, with the episode's absurd title card dropped into the middle of it.
- Seasons 2–4
1 sequence
Modern Family
Fourteen seconds of family photographs sliding into place, and a card. Nothing else.
- Season 1